Reevaluating the imaging definition of tumor progression: perfusion MRI quantifies recurrent glioblastoma tumor fraction, pseudoprogression, and radiation necrosis to predict survival

@inproceedings{Hu2012ReevaluatingTI,
  title={Reevaluating the imaging definition of tumor progression: perfusion MRI quantifies recurrent glioblastoma tumor fraction, pseudoprogression, and radiation necrosis to predict survival},
  author={Leland S. Hu and Jennifer Eschbacher and Joseph E. Heiserman and Amylou C Dueck and William R. Shapiro and Seban Liu and J P Karis and Kris A Smith and Stephen W. Coons and Peter Nakaji and Robert F. Spetzler and Burt G. Feuerstein and Josef Debbins and Leslie C. Baxter},
  booktitle={Neuro-oncology},
  year={2012}
}
INTRODUCTION Contrast-enhanced MRI (CE-MRI) represents the current mainstay for monitoring treatment response in glioblastoma multiforme (GBM), based on the premise that enlarging lesions reflect increasing tumor burden, treatment failure, and poor prognosis. Unfortunately, irradiating such tumors can induce changes in CE-MRI that mimic tumor recurrence, so called post treatment radiation effect (PTRE), and in fact, both PTRE and tumor re-growth can occur together. Because PTRE represents… CONTINUE READING
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