Reentrainment of the circadian pacemaker through three distinct stages.

  title={Reentrainment of the circadian pacemaker through three distinct stages.},
  author={Tiecheng Liu and Jimo Borjigin},
  journal={Journal of biological rhythms},
  volume={20 5},
Circadian rhythms are endogenously generated by a central pacemaker and are synchronized to the environmental LD cycle. The rhythms can be resynchronized, or reentrained, after a shift of the LD cycle, as in traveling across time zones. The authors have performed high-resolution mapping of the pacemaker to analyze the reentrainment process using rat pineal melatonin onset (MT(on)) and melatonin offset (MT(off)) rhythms as markers. Following LD (12:12) delays of 3, 6, and 12 h, MT(on) was phase… CONTINUE READING

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