Reelin signaling directly affects radial glia morphology and biochemical maturation.

@article{Hartfuss2003ReelinSD,
  title={Reelin signaling directly affects radial glia morphology and biochemical maturation.},
  author={Eva Hartfuss and Eckart F{\"o}rster and Hans H. Bock and Michael Anton Hack and Pierre Leprince and Juan Manuel Luque and Joachim Herz and Michael Frotscher and Magdalena G{\"o}tz},
  journal={Development},
  year={2003},
  volume={130 19},
  pages={4597-609}
}
Radial glial cells are characterized, besides their astroglial properties, by long radial processes extending from the ventricular zone to the pial surface, a crucial feature for the radial migration of neurons. The molecular signals that regulate this characteristic morphology, however, are largely unknown. We show an important role of the secreted molecule reelin for the establishment of radial glia processes. We describe a significant reduction in ventricular zone cells with long radial… CONTINUE READING
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