Reelin and its complex involvement in brain development and function.

  title={Reelin and its complex involvement in brain development and function.},
  author={Silvia Lakato{\vs}ov{\'a} and Daniela Ostatn{\'i}kov{\'a}},
  journal={The international journal of biochemistry & cell biology},
  volume={44 9},
Reelin is a neuroprotein with crucial role during neurodevelopment and also in postnatal period. It regulates neuronal migration and positioning in developing neocortex and cerebellar cortex. Postnatally it participates in regulation of dendritic and axonal growth, synaptogenesis, neurotransmission and it contribute to synaptic plasticity necessary for learning and memory functions. Role of Reelin seems to be rather complex, profound research gradually uncovers its further functions. Deficits… CONTINUE READING
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