Redundant role for early growth response transcriptional regulators in thymocyte differentiation and survival.

@article{Carter2007RedundantRF,
  title={Redundant role for early growth response transcriptional regulators in thymocyte differentiation and survival.},
  author={John C. H. Carter and Juliet M Lefebvre and David L Wiest and Warren G. Tourtellotte},
  journal={Journal of immunology},
  year={2007},
  volume={178 11},
  pages={
          6796-805
        }
}
The early growth response (Egr) family of transcriptional regulators consists of four proteins that share highly conserved DNA-binding domains. In many cell types, they are coexpressed and appear to have cooperative roles in regulating gene expression during growth and differentiation. Three Egr proteins, Egr1, Egr2, and Egr3, are induced during thymocyte differentiation in response to pre-TCR signaling, suggesting they may be critical for some aspects of pre-TCR-mediated differentiation… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 25 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 45 REFERENCES

The c-Myc target gene network.

  • Seminars in cancer biology
  • 2006
VIEW 1 EXCERPT