Redundant functions of the genes knirps and knirps-related for the establishment of anterior Drosophila head structures.

@article{GonzalezGaitan1994RedundantFO,
  title={Redundant functions of the genes knirps and knirps-related for the establishment of anterior Drosophila head structures.},
  author={Marcos Gonzalez-Gaitan and Mike Rothe and Ernst A Wimmer and Heike Taubert and Herbert Jaeckle},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1994},
  volume={91 18},
  pages={8567-71}
}
Developmental gene functions of Drosophila are typically characterized by a recognizable mutant phenotype. When molecular probes of such genes were used to isolate homologues, distinct spatially and temporally restricted expression patterns were observed in vertebrates as well. However, corresponding "gene knock-outs" often revealed subtle or no scorable phenotypes, a phenomenon attributed to redundant gene functions. We found that the evolutionarily related genes knirps (kni) and knirps… CONTINUE READING

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