Redundant functions of RIM1alpha and RIM2alpha in Ca(2+)-triggered neurotransmitter release.

@article{Schoch2006RedundantFO,
  title={Redundant functions of RIM1alpha and RIM2alpha in Ca(2+)-triggered neurotransmitter release.},
  author={Susanne Schoch and Tobias Mittelstaedt and Pascal S Kaeser and Daniel Padgett and Nicole Feldmann and Vivien Chevaleyre and Pablo E Castillo and Robert Hammer and Weiping Han and Frank Schmitz and Weichun Lin and Thomas C S{\"u}dhof},
  journal={The EMBO journal},
  year={2006},
  volume={25 24},
  pages={5852-63}
}
Alpha-RIMs (RIM1alpha and RIM2alpha) are multidomain active zone proteins of presynaptic terminals. Alpha-RIMs bind to Rab3 on synaptic vesicles and to Munc13 on the active zone via their N-terminal region, and interact with other synaptic proteins via their central and C-terminal regions. Although RIM1alpha has been well characterized, nothing is known… CONTINUE READING