Redundant and unique roles of coronin proteins in Dictyostelium

@article{Shina2010RedundantAU,
  title={Redundant and unique roles of coronin proteins in Dictyostelium},
  author={Maria Christina Shina and Annette Mueller-Taubenberger and Can Murat {\"U}nal and Michael Schleicher and Michael Steinert and Ludwig Eichinger and Rolf M{\"u}ller and Rosemarie Blau-Wasser and Gernot Gl{\"o}ckner and Angelika A. Noegel},
  journal={Cellular and Molecular Life Sciences},
  year={2010},
  volume={68},
  pages={303-313}
}
Dictyostelium discoideum harbors a short (CRN12) and a long coronin (CRN7) composed of one and two beta-propellers, respectively. They are primarily present in the cell cortex and cells lacking CRN12 (corA−) or CRN7 (corB−) have defects in actin driven processes. We compared the characteristics of a mutant cell line (corA−/corB−) lacking CRN12 and CRN7 with the single mutants focusing on cytokinesis, phagocytosis, chemotaxis and development. Cytokinesis, uptake of small particles, and… CONTINUE READING
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