Reductive Deamination by Benzyne for Deoxy Sugar Synthesis Through a Domino Reaction

Abstract

Benzyne was developed as a reducing agent in the key step of converting amino sugars and ketoses into deoxy sugars, which occur widely in natural products. Many deoxy sugars exhibit antibiotic and anticancer activities, and furthermore, they play essential biological roles. By treatment with CS2 and then Ac2O, amino sugars and ketoses were converted into… (More)
DOI: 10.1002/open.201700050

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Cite this paper

@inproceedings{Hwu2017ReductiveDB, title={Reductive Deamination by Benzyne for Deoxy Sugar Synthesis Through a Domino Reaction}, author={Jih Ru Hwu and Dr. K. B. Chandrasekhar and Kuo Chu Hwang and Chun-Cheng Lin and Jia-Cherng Horng and F Y Shieh}, booktitle={ChemistryOpen}, year={2017} }