Reductions in bone turnover, mineral, and structure associated with mechanical properties of lumbar vertebra and femur in glucocorticoid-treated growing minipigs.

Abstract

The present study was designed to determine the effects of glucocorticoid (GC) on bone turnover, minerals, structure, and bone mechanical properties in minipigs. Six 8-month-old Göttingen minipigs were subcutaneously injected with prednisolone (PN, 0.5 mg/kg body wt (BW)/day, 5 days/week for 26 weeks (Group GC)), 6 were treated with vehicle alone (Group VC… (More)

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Cite this paper

@article{Ikeda2003ReductionsIB, title={Reductions in bone turnover, mineral, and structure associated with mechanical properties of lumbar vertebra and femur in glucocorticoid-treated growing minipigs.}, author={Satoshi Ikeda and Yoshiomi Morishita and Hideki Tsutsumi and M. Ito and Ayako Shiraishi and Shinobu Arita and Shojiro Akahoshi and Ken'ichiro Narusawa and Toshitaka Nakamura}, journal={Bone}, year={2003}, volume={33 5}, pages={779-87} }