Reductions in basal metabolic rate and physical activity contribute to hypothalamic obesity.

@article{Shaikh2008ReductionsIB,
  title={Reductions in basal metabolic rate and physical activity contribute to hypothalamic obesity.},
  author={Mohammed Guftar Shaikh and Richard G. Grundy and Jeremy M. W. Kirk},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2008},
  volume={93 7},
  pages={2588-93}
}
CONTEXT Obesity after hypothalamic damage is often severe and resistant to lifestyle changes. It is postulated that differences in basal metabolic rate (BMR) and physical activity may contribute to hypothalamic obesity (HO). OBJECTIVE Our objective was to investigate the role of energy expenditure, BMR, and physical activity in the etiology of hypothalamic obesity. DESIGN This was a cross-sectional study of three groups of children: those with HO, congenital hypopituitarism (CH), and simple… CONTINUE READING
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