Reduction of the metastatic potential of a RSV-transformed fibroblastic line (B77-AA6 cells) upon transplantation in essential fatty acid-deficient mice.

Metastatic dissemination has been shown to be influenced by dietary lipids. In particular, diets enriched with linoleic acid have been consistently found to be effective in enhancing the metastatic potential of murine mammary tumors. This study explored whether an essential fatty acid (EFA)-deficient host can affect the capacity of a tumor to metastasize to… CONTINUE READING