Reduction of surface-induced inflammatory reaction on PLGA/MPC polymer blend.

@article{Iwasaki2002ReductionOS,
  title={Reduction of surface-induced inflammatory reaction on PLGA/MPC polymer blend.},
  author={Yasuhiko Iwasaki and Shin-ichi Sawada and Kazuhiko Ishihara and Gilson Khang and Hai Bang Lee},
  journal={Biomaterials},
  year={2002},
  volume={23 18},
  pages={3897-903}
}
Poly(lactide-co-glycolide) (PLGA) has been believed to be a good biocompatible material for tissue engineering due to its biodegradability and non-toxicity of the monomer. However, the inflammatory reaction of adherent cells on the surface has not been discussed sufficiently. We hypothesized that the inflammatory reaction of adherent cells on PLGA might occur and could be reduced by blending a 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer (PMEH) with the PLGA. PLGA/PMEH blend membranes… CONTINUE READING

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