Reduction of soluble complement receptor 2/CD21 in systemic lupus erythomatosus and Sjogren's syndrome but not juvenile arthritis.

@article{Masilamani2004ReductionOS,
  title={Reduction of soluble complement receptor 2/CD21 in systemic lupus erythomatosus and Sjogren's syndrome but not juvenile arthritis.},
  author={Madhan Masilamani and Robert L. Nowack and Torsten Witte and Michael Schlesier and Klaus Warnatz and Michael O. Glocker and Hans Hartmut Peter and Harald Illges},
  journal={Scandinavian journal of immunology},
  year={2004},
  volume={60 6},
  pages={625-30}
}
A soluble form of the complement receptor CD21 (sCD21) is shed from the lymphocyte surface. The amount of sCD21 in serum may modulate immunity as sCD21 levels are correlated with several clinical conditions. We report here the serum levels of sCD21 in juvenile arthritis (JA), systemic lupus erythematosus (SLE) and Sjogren's syndrome (SS). Using enzyme-linked immunosorbent assay, we determined sCD21 levels in SLE, SS and JA patients. Mann-Whitney test for nonparametric two-tail P value was… CONTINUE READING