Reduction of serum testosterone levels during chronic glucocorticoid therapy.

@article{MacAdams1986ReductionOS,
  title={Reduction of serum testosterone levels during chronic glucocorticoid therapy.},
  author={M R MacAdams and Richard H. R. White and Bradley E. Chipps},
  journal={Annals of internal medicine},
  year={1986},
  volume={104 5},
  pages={648-51}
}
The effect of chronic glucocorticoid therapy on serum testosterone levels was studied in men aged 67 +/- 4 (SD) years with chronic pulmonary disease. The serum testosterone level was reduced in 14 of 16 patients to a mean value of 211 +/- 93 ng/dL, compared with 449 +/- 111 ng/dL in 11 age- and disease-matched control patients (p less than 0.001). The corticosteroid dosage and the serum testosterone level were inversely related (r = -0.78). Testosterone binding to serum proteins was not… CONTINUE READING
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