Reduction of resuscitation fluid volumes in severely burned patients using ascorbic acid administration: a randomized, prospective study.

@article{Tanaka2000ReductionOR,
  title={Reduction of resuscitation fluid volumes in severely burned patients using ascorbic acid administration: a randomized, prospective study.},
  author={Hisaharu Tanaka and Takayoshi Matsuda and Yasusuke Miyagantani and Tetsuo Yukioka and Hiroharu Matsuda and Shuji Shimazaki},
  journal={Archives of surgery},
  year={2000},
  volume={135 3},
  pages={326-31}
}
HYPOTHESIS High-dose ascorbic acid (vitamin C) therapy (66 mg/kg per hour) attenuates postburn lipid peroxidation, resuscitation fluid volume requirements, and edema generation in severely burned patients. STUDY DESIGN AND SETTING A prospective, randomized study at a university trauma and critical care center in Japan. SUBJECTS AND METHODS Thirty-seven… CONTINUE READING