Reduction of progesterone receptor expression in human cumulus cells at the time of oocyte collection during IVF is associated with good embryo quality.

@article{Hasegawa2005ReductionOP,
  title={Reduction of progesterone receptor expression in human cumulus cells at the time of oocyte collection during IVF is associated with good embryo quality.},
  author={Junichi Hasegawa and Atsushi Yanaihara and Shinji Iwasaki and Yukiko Otsuka and Momoko Negishi and Tomoko Akahane and Takashi Okai},
  journal={Human reproduction},
  year={2005},
  volume={20 8},
  pages={
          2194-200
        }
}
BACKGROUND It has been reported that the progesterone receptor (PR) level is transiently increased within the follicle by LH stimulation and controls cumulus cells in follicles and oocyte maturation. The purpose of this study was to predict developmental competence of human oocytes during IVF via analysis of PR in cumulus cells surrounding mature oocytes. METHODS Prior to oocyte retrieval, the follicular diameter was measured and follicular fluid was collected from each mature follicle… CONTINUE READING

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