Reduction of oxidative stress marker levels by anti-TNF-alpha antibody, infliximab, in patients with rheumatoid arthritis.

@article{Kageyama2008ReductionOO,
  title={Reduction of oxidative stress marker levels by anti-TNF-alpha antibody, infliximab, in patients with rheumatoid arthritis.},
  author={Yasunori Kageyama and M Takahashi and Tetsuya Ichikawa and Eiji Torikai and Akira Nagano},
  journal={Clinical and experimental rheumatology},
  year={2008},
  volume={26 1},
  pages={73-80}
}
OBJECTIVE The aim of this study was to evaluate the effects of anti-TNF-alpha antibody, infliximab, on oxidative stress markers representing DNA damage, lipid peroxidation, and glycoxidation. METHODS Twenty-three RA patients underwent infliximab treatment and were analyzed for 30 weeks. Six patients who experienced side effects and one patient who had a reduced efficacy of infliximab were discontinued the infliximab treatment at 30-54 weeks. Sixteen patients were analyzed for 54 weeks. The… CONTINUE READING
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