Reduction of oxidative stress and liver injury following silymarin and praziquantel treatment in mice with Mesocestoides vogae (Cestoda) infection.

@article{Velebn2010ReductionOO,
  title={Reduction of oxidative stress and liver injury following silymarin and praziquantel treatment in mice with Mesocestoides vogae (Cestoda) infection.},
  author={Samuel Velebn{\'y} and G. Hr{\vc}kov{\'a} and A. K{\"o}nigov{\'a}},
  journal={Parasitology international},
  year={2010},
  volume={59 4},
  pages={
          524-31
        }
}
  • Samuel Velebný, G. Hrčková, A. Königová
  • Published 2010
  • Biology, Medicine
  • Parasitology international
  • Oxidative stress is a common mechanism contributing to hepatic damage and fibrogenesis in a variety of liver disorders. The liver is the target organ for many parasitic infections, hence there is a great demand for the development of novel treatment strategies. In the present study conducted on mice infected with larval stage of Mesocestoides vogae, we investigated effects of therapy with praziquantel (PZQ) alone and in combination with silymarin on liver GSH content, lipid peroxidation and… CONTINUE READING
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