Reduction of opioid-withdrawal symptoms with quetiapine.

  title={Reduction of opioid-withdrawal symptoms with quetiapine.},
  author={Harold B. Pinkofsky and Ann M Hahn and Frances A. Campbell and John Rueda and Dennis C. Daley and Antoine B. Douaihy},
  journal={The Journal of clinical psychiatry},
  volume={66 10},
OBJECTIVE To determine the utility of quetiapine in a population undergoing ambulatory detoxification from opioids. METHOD Medications utilized in our outpatient clinic for opioid withdrawal were evaluated for quality-assurance purposes. The treatment regimen generally included clonidine, hydroxyzine, trazodone, diphenoxylate/atropine, and sometimes chlordiazepoxide. Patients were also initially given eight 25-mg tablets of quetiapine and instructed to take 1 or 2 tablets every 4 hours as… CONTINUE READING


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