Reduction of malachite green to leucomalachite green by intestinal bacteria.

@article{Henderson1997ReductionOM,
  title={Reduction of malachite green to leucomalachite green by intestinal bacteria.},
  author={Alexandra L. Henderson and Thomas C. Schmitt and Thomas M. Heinze and Carl Cerniglia},
  journal={Applied and environmental microbiology},
  year={1997},
  volume={63 10},
  pages={
          4099-101
        }
}
Intestinal microfloras from human, rat, mouse, and monkey fecal samples and 14 pure cultures of anaerobic bacteria representative of those found in the human gastrointestinal tract metabolized the triphenylmethane dye malachite green to leucomalachite green. The reduction of malachite green to the leuco derivative suggests that intestinal microflora could play an important role in the metabolic activation of the triphenylmethane dye to a potential carcinogen. 

Citations

Publications citing this paper.
SHOWING 1-10 OF 38 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 22 REFERENCES

Optimization of a liquid chromatographic method for determination of malachite green and its metabolites in fish tissues

  • S. M. Plakas, K. R. ElSaid, G. R. Stehly, J. E. Roybal
  • J. Assoc. Off. Anal. Chem. Int
  • 1995
Highly Influential
6 Excerpts

Similar Papers

Loading similar papers…