Reduction of insulin dose on changing diabetic children from standard to monocomponent insulins.

Abstract

21 diabetic children requiring greater than 50 units of standard insulin daily were changed to a monocomponent insulin. During the 3 months before the change the insulin dose had risen significantly from a mean of 70 to a mean of 77 units daily. During the 3 months after the change the dose fell significantly to a mean of 53 units daily. This decrease in insulin requirement was associated with a general improvement in diabetic control. This was assessed clinically and measured in 10 children by an analysis of home urine tests and in 8 children by an analysis of 24-hour urine glucose excretion.

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@article{Griffin1979ReductionOI, title={Reduction of insulin dose on changing diabetic children from standard to monocomponent insulins.}, author={Nick Griffin and Murray A Smith and J. David Baum}, journal={Archives of disease in childhood}, year={1979}, volume={54 2}, pages={123-6} }