Reduction of free immunoglobulin light chains using adsorption properties of hemodiafiltration with endogenous reinfusion.

@article{Testa2010ReductionOF,
  title={Reduction of free immunoglobulin light chains using adsorption properties of hemodiafiltration with endogenous reinfusion.},
  author={Angelo Testa and Thomas Dejoie and Didier Lecarrer and Marylou Wratten and Luisa Sereni and Jean Louis Renaux},
  journal={Blood purification},
  year={2010},
  volume={30 1},
  pages={34-6}
}
In this work we investigated the acute effects of hemodiafiltration with endogenous reinfusion (HFR therapy) on the removal of free immunoglobulin light chains (FIgLCs), which may be considered members of the family of uremic toxins. In two groups of patients - group 1 (polyclonal FIgLCs production) and group 2 (monoclonal plasma cell proliferative disorders), we analyzed the pre- and postdialysis levels of kappa- and lambda-chains. In group 1 we observed a significant reduction of FIgLCs (p… CONTINUE READING

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