Reduction of free fatty acids by acipimox enhances the growth hormone (GH) responses to GH-releasing peptide 2 in elderly men.

@article{Dam2000ReductionOF,
  title={Reduction of free fatty acids by acipimox enhances the growth hormone (GH) responses to GH-releasing peptide 2 in elderly men.},
  author={P. Sytze van Dam and H E C Smid and Wouter R. De Vries and M Niesink and Ellen Bolscher and Evert J. Waasdorp and Carlos Di{\'e}guez and Felipe F F Casanueva and H. P. F. Koppeschaar},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2000},
  volume={85 12},
  pages={4706-11}
}
GH release is increased by reducing circulating free fatty acids (FFAs). Aging is associated with decreased plasma GH concentrations. We evaluated GH releasing capacity in nine healthy elderly men after administration of GH-releasing peptide 2 (GHRP-2), with or without pretreatment with the antilipolytic drug acipimox, and compared the GHRP-2-induced GH… CONTINUE READING