Reduction of food intake by cholecystokinin requires activation of hindbrain NMDA-type glutamate receptors.

@article{Wright2011ReductionOF,
  title={Reduction of food intake by cholecystokinin requires activation of hindbrain NMDA-type glutamate receptors.},
  author={Jason S. Wright and Carlos Ja Campos and Thiebaut Herzog and Mihai Covasa and Krzysztof Czaja and Robert C. Ritter},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  year={2011},
  volume={301 2},
  pages={
          R448-55
        }
}
Intraperitoneal injection of CCK reduces food intake and triggers a behavioral pattern similar to natural satiation. Reduction of food intake by CCK is mediated by vagal afferents that innervate the stomach and small intestine. These afferents synapse in the hindbrain nucleus of the solitary tract (NTS) where gastrointestinal satiation signals are processed. Previously, we demonstrated that intraperitoneal (IP) administration of either competitive or noncompetitive N-methyl-d-aspartate (NMDA… CONTINUE READING

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