Reduction of enzyme levels by propranolol after acute myocardial infarction.

@article{Peter1978ReductionOE,
  title={Reduction of enzyme levels by propranolol after acute myocardial infarction.},
  author={Thomas C. Peter and Robin M Norris and Eric D. Clarke and Ming K. Heng and Bramah N. Singh and Bryn Williams and David R Howell and P K Ambler},
  journal={Circulation},
  year={1978},
  volume={57 6},
  pages={1091-5}
}
The effect of propranolol (0.1 mg/kg intravenously followed by 320 mg given over 27 hour orally) on serum levels of creatine kinase enzyme was studied in a randomized trial involving 95 patients seen within 12 hours of onset of symptoms of uncomplicated myocardial infarction. In 15 patients who were treated with propranolol within 4 hours of onset, and who eventually developed pathological Q waves, peak measured enzyme levels were 27% (P less than 0.0125) lower than in 19 control patients who… CONTINUE READING