Reduction of enucleation-induced metastasis in intraocular melanoma by periorbital irradiation.

@article{Sanborn1987ReductionOE,
  title={Reduction of enucleation-induced metastasis in intraocular melanoma by periorbital irradiation.},
  author={George E. Sanborn and Phuongmai Nguyen and John W. Gamel and Jerry Y. Niederkorn},
  journal={Archives of ophthalmology},
  year={1987},
  volume={105 9},
  pages={1260-4}
}
The optimum treatment of malignant choroidal melanoma remains controversial. Some authors have hypothesized that enucleation promotes metastatic disease. This hypothesis has been demonstrated in the B16F10 melanoma mouse model. The present study used this model to examine the effect of external beam irradiation as a means of reducing metastases induced by… CONTINUE READING