Reduction of elevated plasma osteopontin levels with resection of non-small-cell lung cancer.

@article{Blasberg2010ReductionOE,
  title={Reduction of elevated plasma osteopontin levels with resection of non-small-cell lung cancer.},
  author={J. Blasberg and H. Pass and C. Goparaju and R. Flores and Suzie Lee and J. Donington},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={2010},
  volume={28 6},
  pages={
          936-41
        }
}
  • J. Blasberg, H. Pass, +3 authors J. Donington
  • Published 2010
  • Medicine
  • Journal of clinical oncology : official journal of the American Society of Clinical Oncology
PURPOSE Plasma osteopontin (OPN) levels in advanced non-small-cell lung cancer (NSCLC) correlate with therapeutic response and survival, but the utility of plasma OPN for diagnosis and monitoring of early-stage NSCLC has not been investigated. We hypothesize that plasma OPN levels are elevated in early-stage NSCLC and decrease with resection. PATIENTS AND METHODS Presurgery plasma OPN levels (in ng/mL) were measured by enzyme-linked immunosorbent assay (ELISA) in a discovery set of 60 patients… Expand
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