Reduction of cystic cavity, promotion of axonal regeneration and sparing, and functional recovery with transplanted bone marrow stromal cell-derived Schwann cells after contusion injury to the adult rat spinal cord.

@article{Someya2008ReductionOC,
  title={Reduction of cystic cavity, promotion of axonal regeneration and sparing, and functional recovery with transplanted bone marrow stromal cell-derived Schwann cells after contusion injury to the adult rat spinal cord.},
  author={Yukio Someya and Masao Koda and Mari Dezawa and Tomoko Kadota and Masayuki Hashimoto and Takahito Kamada and Yutaka Nishio and Ryo Kadota and Chikato Mannoji and Tomohiro Miyashita and Akihiko Okawa and Katsunori Yoshinaga and Masashi Yamazaki},
  journal={Journal of neurosurgery. Spine},
  year={2008},
  volume={9 6},
  pages={600-10}
}
OBJECT The authors previously reported that Schwann cells (SCs) could be derived from bone marrow stromal cells (BMSCs) in vitro and that they promoted axonal regeneration of completely transected rat spinal cords in vivo. The aim of the present study is to evaluate the efficacy of transplanted BMSC-derived SCs (BMSC-SCs) in a rat model of spinal cord contusion, which is relevant to clinical spinal cord injury. METHODS Bone marrow stromal cells were cultured as plastic-adherent cells from the… CONTINUE READING

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