Reduction of cyclosporine after introduction of mycophenolate mofetil improves chronic renal dysfunction in heart transplant recipients--the IMPROVED multi-centre study.

Abstract

AIMS This comparative prospective multi-centre study evaluated efficacy and safety of cyclosporine A downtitration in heart transplant recipients with chronic renal dysfunction potentially attributable to cyclosporine (n=161). METHODS In the intervention arm (n=109, recruited from 9 centres), mycophenolate mofetil was introduced de novo or substituting… (More)

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@article{Angermann2004ReductionOC, title={Reduction of cyclosporine after introduction of mycophenolate mofetil improves chronic renal dysfunction in heart transplant recipients--the IMPROVED multi-centre study.}, author={Christiane E. Angermann and Stefan St{\"{o}rk and Angelika Costard-Jaeckle and Thomas J. Dengler and Uwe Siebert and Gero Tenderich and Axel Rahmel and Ernst Schwarz and Herbert Naegele and Florian Matthias Wagner and Bernd Haaff and Klaus Pethig}, journal={European heart journal}, year={2004}, volume={25 18}, pages={1626-34} }