Reduction of cortical volume in schizophrenia on magnetic resonance imaging

@article{Harvey1993ReductionOC,
  title={Reduction of cortical volume in schizophrenia on magnetic resonance imaging},
  author={Ian Harvey and Maria A. Ron and George H. du Boulay and D. A. G. Wicks and S. Lewis and Robin M. Murray},
  journal={Psychological Medicine},
  year={1993},
  volume={23},
  pages={591 - 604}
}
Synopsis The MRI scans of 48 schizophrenic patients, fulfilling RDC criteria, were compared to those of 34 healthy controls matched for age, ethnicity and parental social class. The volume of the frontal and anterior parietal lobes was significantly reduced in the schizophrenic group as a result of a selective decrease in cortical volume, with a corresponding increase in the volume of sulcal fluid. Reduction in the volume of the temporal grey matter was more marked on the right, but was not in… 

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