Reduction of coronary flow reserve in areas with and without ischemia on stress perfusion imaging in patients with coronary artery disease: a study using oxygen 15-labeled water PET.

@article{Yoshinaga2003ReductionOC,
  title={Reduction of coronary flow reserve in areas with and without ischemia on stress perfusion imaging in patients with coronary artery disease: a study using oxygen 15-labeled water PET.},
  author={Keiichiro Yoshinaga and Chietsugu Katoh and Kazuyuki Noriyasu and Yasuyoshi Iwado and Hideto Furuyama and Yoshinori Ito and Yuji Kuge and Tetsuro Kohya and Akira Kitabatake and N. Tamaki},
  journal={Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology},
  year={2003},
  volume={10 3},
  pages={275-83}
}
BACKGROUND Myocardial perfusion single photon emission computed tomography (SPECT) occasionally fails to detect coronary stenosis in patients with coronary artery disease (CAD). We evaluated coronary flow reserve (CFR) using oxygen 15-labeled water in areas with and without ischemia on technetium 99m tetrofosmin stress perfusion SPECT in patients with angiographically documented CAD. METHODS AND RESULTS Twenty-seven patients with CAD and eleven age-matched normal subjects were studied… CONTINUE READING

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