Reduction of chromogranin A and B but not C in the cerebrospinal fluid in subjects with schizophrenia.

@article{Landn1999ReductionOC,
  title={Reduction of chromogranin A and B but not C in the cerebrospinal fluid in subjects with schizophrenia.},
  author={Mikael Land{\'e}n and B. Grenfeldt and Pia Davidsson and Mats Stridsberg and Bj{\"o}rn Regland and Carl G Gottfries and K Blennow},
  journal={European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology},
  year={1999},
  volume={9 4},
  pages={311-5}
}
The granins (secretogranins/chromogranins) are a family of soluble proteins stored and released from the secretory large dense-core vesicles of the synapse. Schizophrenia is a common and devastating brain disorder. Although the aetiology of schizophrenia is unknown, data are accumulating that synaptic disturbance or damage may be of importance. The objective of this study was to compare the levels of chromogranin A, B and C in the cerebrospinal fluid (CSF) of patients with schizophrenia and… CONTINUE READING
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