Reduction of cerebral infarct size by non-competitive AMPA antagonists in rats subjected to permanent and transient focal ischemia

@article{Matucz2004ReductionOC,
  title={Reduction of cerebral infarct size by non-competitive AMPA antagonists in rats subjected to permanent and transient focal ischemia},
  author={{\'E}va Matucz and K. M{\'o}ricz and G. Gigler and A. Sim{\'o} and G. Sz{\'e}n{\'a}si},
  journal={Brain Research},
  year={2004},
  volume={1019},
  pages={210-216}
}
Antagonists of 2-amino-3(3-hydroxy-5-methyl-4-isoxazolyl) propionic acid (AMPA) receptors can considerably reduce brain damage after cerebral ischemia, but effectiveness of selective AMPA antagonists has been questioned recently. Therefore, we evaluated the antiischemic efficacy of [+/-]-7-acetyl-5-[4-aminophenyl]-7,8-dihydro-8-cyano-8-methyl-9H-1,3-dioxolo-[4,5-h]-2,3-benzodiazepine (EGIS-8332) and GYKI 53405, two selective, non-competitive AMPA antagonists in two rat models of focal cerebral… Expand
27 Citations
Cell-permeant calcium buffer induced neuroprotection after cortical devascularization
  • 9
...
1
2
3
...

References

SHOWING 1-10 OF 38 REFERENCES
GYKI 53665, a 2,3-benzodiazepine, non-competitively protects cultured neurones against AMPA toxicity.
  • 22
Short Therapeutic Window for MK-801 in Transient Focal Cerebral Ischemia in Normotensive Rats
  • 86
Calcium Accumulation following Middle Cerebral Artery Occlusion in Stroke-Prone Spontaneously Hypertensive Rats
  • 25
  • PDF
...
1
2
3
4
...