Reduction of blood loss with tranexamic acid in primary total hip replacement surgery.

  title={Reduction of blood loss with tranexamic acid in primary total hip replacement surgery.},
  author={Michael Claeys and Nick Vermeersch and Patrick Haentjens},
  journal={Acta chirurgica Belgica},
  volume={107 4},
BACKGROUND In this prospective, placebo-controlled, double-blind, randomized clinical trial, we investigated the effect of a single preoperative bolus dose of tranexamic acid (15 mg/kg) on perioperative blood losses and packed cell transfusion requirements in patients scheduled for primary unilateral total hip replacement surgery for degenerative osteoarthrosis. PATIENTS AND METHODS 40 patients were randomized to receive either 15 mg/kg tranexamic acid (TA group) or an equal volume of saline… CONTINUE READING


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