Reduction of blood loss using high-dose aprotinin in major orthopaedic surgery: a prospective, double-blind, randomised and placebo-controlled study.

Abstract

We have investigated in a prospective,randomised placebo-controlled study the effect of high-dose aprotinin on blood loss in patients admitted for major surgery (revision arthroplasty of the hip or knee, or for resection of a soft-tissue sarcoma). The mean intraoperative blood loss was reduced from 1957 ml in the control group to 736 ml in the aprotinin… (More)

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@article{Jeserschek2003ReductionOB, title={Reduction of blood loss using high-dose aprotinin in major orthopaedic surgery: a prospective, double-blind, randomised and placebo-controlled study.}, author={R. Jeserschek and H. E. Clar and Clemens Aigner and Peter Rehak and Beatrice Primus and Reinhard Windhager}, journal={The Journal of bone and joint surgery. British volume}, year={2003}, volume={85 2}, pages={174-7} }