Reduction of apparent indicators of liver cirrhosis in rats by the arachidonate lipoxygenase inhibitor BW755C.

@article{Mourelle1987ReductionOA,
  title={Reduction of apparent indicators of liver cirrhosis in rats by the arachidonate lipoxygenase inhibitor BW755C.},
  author={Marisa Mourelle and J L Amezcua and V{\'i}ctor M P{\'e}rez-Alvarez},
  journal={European journal of pharmacology},
  year={1987},
  volume={134 2},
  pages={175-80}
}
We have compared the effects of BW755C, a dual inhibitor of the arachidonic acid cyclo-oxygenase and lipoxygenase, with the effects of colchicine and indomethacin on the reversion of the biochemical and histochemical signs of rat liver cirrhosis. This was induced by i.p. administration of CCl4 for 11 weeks. At this point the rats were divided into four… CONTINUE READING