Reduction of adverse effects of indomethacin by anti-allergic drugs in rat stomachs.

@article{Ohara1992ReductionOA,
  title={Reduction of adverse effects of indomethacin by anti-allergic drugs in rat stomachs.},
  author={Ayako Ohara and Satoru Sugiyama and Hiroshi Hoshino and Eiji Hamajima and Hidemi Goto and Yoshihisa Tsukamoto and Takayuki Ozawa},
  journal={Arzneimittel-Forschung},
  year={1992},
  volume={42 9},
  pages={1115-8}
}
This study was designed to elucidate the role of leukotrienes (LT) in indomethacin-induced gastric ulcers in relation to effects of clinically available anti-allergic drugs, azelastine (Azeptin, CAS 58581-89-8) and oxatomide (CAS 60607-34-3). Azelastine (2 mg/kg) or oxatomide (30 mg/kg) was administered intragastrically once 15 min before intragastrical… CONTINUE READING