Reduction of Dnq and ß‐lap by Nqo1 in Vitro

    Abstract

    Supplemental Table 1. To further understand the enhanced potency of DNQ relative to ß‐lap, the ability of these compounds to act as substrates in vitro for NQO1 was assessed (via loss of NADH signal at 340 nm) according to the method of Pink et al. JBC, 2000 (see ref #10). The results show that at concentrations of 1 μmol/L NQO1 processes DNQ approximately… (More)

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