• Corpus ID: 4517674

Reduction of Combinatorial Space of Adjustable Kinetic Parameters of Biochemical Network Models in Optimisation Task

  title={Reduction of Combinatorial Space of Adjustable Kinetic Parameters of Biochemical Network Models in Optimisation Task},
  author={Ivars Mozga and Egils Stalidzans},
The search for minimal set of adjustable parameters through optimising a kinetic model of biochemical networks is needed in industrial biotechnology to increase the productivity of industrial organism strains while keeping low the chance of causing unwanted side effects of implemented changes. As the search for minimal set of adjustable parameters is of combinatorial nature, the search space becomes very large even at relatively small number of parameters. The presented approach of search space… 

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