Reduction in microalbuminuria in diabetics by eicosapentaenoic acid ethyl ester

@article{Hamazaki1990ReductionIM,
  title={Reduction in microalbuminuria in diabetics by eicosapentaenoic acid ethyl ester},
  author={Tomohito Hamazaki and Eisuke Takazakura and Kenzo Osawa and Masaharu Urakaze and Saburo Yano},
  journal={Lipids},
  year={1990},
  volume={25},
  pages={541-545}
}
Eicosapentaenoic acid (EPA) ethyl ester (1.8 g/d) was administered to 16 diabetic patients (5 insulin-dependent and 11 noninsulin-dependent diabetics) for 6 mon. EPA in total plasma fatty acids increased from 4.0±2.4 mol% (mean±SD) to 7.5±3.1 mol% (p<0.001). Albumin excretion, measured with spot urine, was significantly reduced from 65 to 36 mg/g creatinine (geometric means, p<0.001). Fasting blood sugar levels, glycohemoglobin, body weight and blood pressure did not change significantly during… CONTINUE READING