Reduction in injection pain with botulinum toxin type B further diluted using saline with preservative: a double-blind, randomized controlled trial.

@article{Laborde2003ReductionII,
  title={Reduction in injection pain with botulinum toxin type B further diluted using saline with preservative: a double-blind, randomized controlled trial.},
  author={S van Laborde and Jeffrey S. Dover and Megan K Moore and Brigitte Stewart and Kenneth A. Arndt and M Alam},
  journal={Journal of the American Academy of Dermatology},
  year={2003},
  volume={48 6},
  pages={875-7}
}
BACKGROUND Injection with botulinum A exotoxin reconstituted with preserved saline has been shown to be less uncomfortable than injection with the same toxin reconstituted with preservative-free saline. OBJECTIVE We sought to determine whether injection with botulinum toxin type B is similarly less painful when preservative-containing saline is used to further dilute the product. METHODS We conducted a double-blind, randomized controlled trial. A total of 15 consecutive adult patients… CONTINUE READING

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