Reduction in gram-positive pneumonia and antibiotic consumption following the use of a SDD protocol including nasal and oral mupirocin.

@article{Nardi2001ReductionIG,
  title={Reduction in gram-positive pneumonia and antibiotic consumption following the use of a SDD protocol including nasal and oral mupirocin.},
  author={Giuseppe Nardi and Adriana Di Silvestre and Amato de Monte and Daniele Massarutti and Antonella Proietti and M Grazia Troncon and L Lesa and M Zussino},
  journal={European journal of emergency medicine : official journal of the European Society for Emergency Medicine},
  year={2001},
  volume={8 3},
  pages={203-14}
}
The objective of this prospective, randomized, double-blind study was to evaluate the effect of the addition of mupirocin to the 'classical' topical SDD regimen (tobramycin 80 mg, polymyxin E 100 mg, amphotericin B 500 mg) on the development of ICU-acquired infections due to gram-positive bacteria. The study was carried out in an intensive care unit (ICU) of a 1400-bed community hospital. All patients admitted to the ICU during a 16-month period, who were expected to require mechanical… CONTINUE READING

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Treatment of Staphylococcus aureus colonization and prophylaxis for infection with topical intranasal mupirocin: an evidence-based review.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America • 2003
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