Reduction in corpora lutea number in obese melanocortin-4-receptor-deficient mice


Obese melanocortin-4-receptor-deficient (MC4R-/-) male mice are reported to have erectile dysfunction, while homozygous MC4R-/- female mice are apparently fertile. A recently established obese mouse strain, carrying an inactivating mutation in the MC4R gene, revealed difficulties in breeding for the homozygous female mice. This prompted us to determine the… (More)
DOI: 10.1186/1477-7827-7-24

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