Reduction in carotid arterial wall thickness using lovastatin and dietary therapy: a randomized controlled clinical trial.

@article{Hodis1996ReductionIC,
  title={Reduction in carotid arterial wall thickness using lovastatin and dietary therapy: a randomized controlled clinical trial.},
  author={Howard N. Hodis and Wendy J. Mack and Laurie D Labree and Robert H. Selzer and C. R. Liu and Peter Alaupovic and Helenann H. Kwong-Fu and Stanley Paul Azen},
  journal={Annals of internal medicine},
  year={1996},
  volume={124 6},
  pages={548-56}
}
Controlled clinical trials to assess the effects of therapy for atherosclerosis have generally used either clinical cardiovascular events or serial arterial imaging as end points. Serial coronary angiographic assessment of lesion change has been the most commonly used end point in arterial imaging trials [1]. Evidence now indicates that high-resolution B-mode ultrasonographic measurement of the combined thickness of the carotid arterial intima-media complex is a reliable end point for lipid… CONTINUE READING

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