Reduction in airway hyperresponsiveness to methacholine by the application of RF energy in dogs.

@article{Danek2004ReductionIA,
  title={Reduction in airway hyperresponsiveness to methacholine by the application of RF energy in dogs.},
  author={Christopher J Danek and Charles M. Lombard and Donald L. Dungworth and Paul G. Cox and J. D. R. Miller and Michael J Biggs and Thomas M. Keast and Bryan E Loomas and William J Wizeman and James C. Hogg and Alan R. Leff},
  journal={Journal of applied physiology},
  year={2004},
  volume={97 5},
  pages={1946-53}
}
We delivered controlled radio frequency energy to the airways of anesthetized, ventilated dogs to examine the effect of this treatment on reducing airway narrowing caused by a known airway constrictor. The airways of 11 dogs were treated with a specially designed bronchial catheter in three of four lung regions. Treatments in each of the three treated lung regions were controlled to a different temperature (55, 65, and 75 degrees C); the untreated lung region served as a control. We measured… CONTINUE READING