Reduction by naproxen of excessive menstrual bleeding in women using intrauterine devices.

@article{Davies1981ReductionBN,
  title={Reduction by naproxen of excessive menstrual bleeding in women using intrauterine devices.},
  author={A. J. Davies and Andy B. Anderson and A c Turnbull},
  journal={Obstetrics and gynecology},
  year={1981},
  volume={57 1},
  pages={74-8}
}
Thirty-four patients using intrauterine contraceptive devices and experiencing excessive menstrual bleeding (more than 80 ml average loss for 2 cycles) were treated with the prostaglandin synthetase inhibitor naproxen. The trial was conducted according to a double-blind placebo-controlled crossover design. Each patient received 2 of 3 treatments: naproxen in high dose (1250 mg/day for 5 days), naproxen in low dose (500-mg loading dose, than 750 mg/day for 5 days), or placebo. Each treatment was… CONTINUE READING