Reducing the risk of transmitting genital herpes: advances in understanding and therapy

@article{Leone2005ReducingTR,
  title={Reducing the risk of transmitting genital herpes: advances in understanding and therapy},
  author={Peter A. Leone},
  journal={Current Medical Research and Opinion},
  year={2005},
  volume={21},
  pages={1577 - 1582}
}
  • P. Leone
  • Published 5 September 2005
  • Medicine
  • Current Medical Research and Opinion
ABSTRACT Background: This review considers the epidemiology and impact of genital herpes, discusses how herpes simplex virus‐2 (HSV‐2) is transmitted, and reviews data on methods of reducing the risk of HSV transmission. Scope: Information for the paper was identified through multiple PubMed searches. Information in the section on interventions was identified through PubMed searches using several pairs of key words (herpes and transmission, herpes and treatment, herpes and antiviral, herpes and… 
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References

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TLDR
Once-daily suppressive therapy with valacyclovir significantly reduces the risk of transmission of genital herpes among heterosexual, HSV-2-discordant couples.
Genital herpes and public health: addressing a global problem.
TLDR
Doctors and patients must be aware of the subclinical presentation of genital herpes and the potential these patients have for transmitting HSV, and researchers must evaluate the performance of type-specific tests and strategies to prevent transmission.
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TLDR
To determine whether acyclovir suppresses subclinical shedding of HSV-2 in the genital tract, a placebo-controlled, crossover trial of suppressive acyClovir therapy in women with recently acquired genital herpes is conducted.
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TLDR
The majority of patients with genital herpes simplex virus infections have symptoms and signs unrecognised by either themselves or their clinicians, and oral antiviral treatment should be given for primary or first episode genital herpes.
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TLDR
The traditional view of genital herpes is that it is a low prevalence sexually transmitted disease, principally caused by herpes simplex virus type 2, but recent data from epidemiological, natural course, and antiviral studies suggest that this advice may be misleading.
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TLDR
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TLDR
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TLDR
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TLDR
Efforts to identify individuals with undiagnosed genital herpes and to instruct these individuals concerning the risk of disease transmission in the presence of lesions are needed if the rate of transmission is to be decreased; however, methods designed to deerease the rates of transmission by asymptomatic individuals must also be evaluated.
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TLDR
The frequency of viral shedding in men with genital herpes appears comparable with that in women, and the shedding rate amongMen with genital HSV-2 was significantly higher than among men with herpes simplex virus type 2 infection.
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