Reducing the number of sputum samples examined and thresholds for positivity: an opportunity to optimise smear microscopy.

@article{Bonnet2007ReducingTN,
  title={Reducing the number of sputum samples examined and thresholds for positivity: an opportunity to optimise smear microscopy.},
  author={Maryline M B Bonnet and Andy Ramsay and Laramie Gagnidze and Willie A. Githui and Philippe J Guerin and Frederic Varaine},
  journal={The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease},
  year={2007},
  volume={11 9},
  pages={953-8}
}
SETTING Urban health clinic, Nairobi. OBJECTIVE To evaluate the impact on tuberculosis (TB) case detection and laboratory workload of reducing the number of sputum smears examined and thresholds for diagnosing positive smears and positive cases. DESIGN In this prospective study, three Ziehl-Neelsen stained sputum smears from consecutive pulmonary TB suspects were examined blind. The standard approach (A), > or = 2 positive smears out of 3, using a cut-off of 10 acid-fast bacilli (AFB)/100… CONTINUE READING

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