Reducing effect of the positive allosteric modulator of the GABAB receptor, GS39783, on alcohol self-administration in alcohol-preferring rats

@article{Maccioni2007ReducingEO,
  title={Reducing effect of the positive allosteric modulator of the GABAB receptor, GS39783, on alcohol self-administration in alcohol-preferring rats},
  author={P. Maccioni and D. Pes and Alessandro Orr{\`u} and W. Froestl and G. Gessa and Mauro A. M. Carai and G. Colombo},
  journal={Psychopharmacology},
  year={2007},
  volume={193},
  pages={171-178}
}
  • P. Maccioni, D. Pes, +4 authors G. Colombo
  • Published 2007
  • Psychology, Medicine
  • Psychopharmacology
  • Rationale and objectivesThe positive allosteric modulator of the GABAB receptor, GS39783, has recently been found to suppress acquisition and maintenance of alcohol drinking behavior in selectively bred Sardinian alcohol-preferring (sP) rats exposed to the standard, homecage two-bottle “alcohol vs water” choice regimen. The present study was designed to extend the characterization of the “anti-alcohol” effects of GS39783 to oral self-administration of alcohol under an operant procedure… CONTINUE READING
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